Toxicity is extremely rare following administration of recommended dose. Nevertheless, massive overdose of acetaminophen may adversely affect the liver of some people and signs or symptoms of overdose may be delayed for up to one week following ingestion. Nevertheless, liver damage is largely reversible if the patient is treated early, thus immediately medical management is required in the event of overdose, even if symptoms of overdose are not present. Acetaminophen overdose may cause liver failure.
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